General Demonavenger

How to properly use Demonic Blast/Blood Feast? I was just wondering how to exactly incorporate Demonic Blast/Blood Feast while bossing in particular. You get the maximum damage output if you hold down the skill for 7 seconds. However, to hold down the button while having to use your other skills and movement in a fast paced bossing session can be very difficult. I wish you can simply press the button once, let it charge up, then press it again to release. That would make things much more easier. Anyways, are there any tips or tricks to overcoming this hurdle?